Phosphatidylserine Powder

CAS No.:84776-79-4

Content:500g/Bag

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What is Phosphatidylserine?

Phosphatidylserine (PS) is a phospholipid—a key structural component of cell membranes—distinguished by its hydrophilic serine head group and hydrophobic fatty acid tails. Naturally abundant in the brain (comprising 10–20% of total phospholipids in neuronal membranes), PS plays a pivotal role in maintaining membrane fluidity, facilitating cell signaling, and supporting neurotransmitter function. Beyond its endogenous presence, phosphatidylserine powder can be obtained via advanced purification and extraction technologies from soybeans and sunflower seeds, enabling purity ranging from 50% to 99%.
Recognized for its role in brain health, phosphatidylserine has already gained FDA certificates, being approved to use in dietary supplements with "cognitive support" claims. Recently, with the phenomena of aging population, rising awareness of neurodegenerative diseases, and expanding applications in functional foods, infant nutrition supplements, and pharmaceuticals.

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Phosphatidylserine Benefits

Superior Bioavailability & Cellular Uptake Enhance Cognitive Function & Memory

Phosphatidylesine is most widely studied for its ability to support memory, attention, and executive function—particularly in aging populations. By maintaining neuronal membrane fluidity, it improves the efficiency of neurotransmitter receptors (e.g., for acetylcholine, a key memory-related neurotransmitter) and promotes synaptic plasticity (the brain’s ability to form new connections). A 2023 meta-analysis of 12 randomized controlled trials, published in Nutrients, found that daily supplementation with 100–300mg of PS improved verbal memory scores by 15–20% in adults aged 50–70 with age-related memory decline. For individuals with mild cognitive impairment (MCI), long-term PS intake (6 months or more) slowed cognitive deterioration by 30% compared to placebo, according to a study in The American Journal of Clinical Nutrition.
Regulate Mood & Reduce StressPhosphatidylserine moudulates the hypothalamic-pituitary-adrenal (HPA) axis—the body’s primary stress response system—by lowering circulating levels of cortisol (the "stress hormone"). Clinical trials show that 200mg of PS taken daily for 4 weeks reduced salivary cortisol levels by 18–25% in healthy adults undergoing chronic stress (e.g., work-related pressure). In a 2022 study of 120 adults with mild anxiety, PS supplementation improved mood scores (measured via the Profile of Mood States) by 19% and reduced self-reported anxiety symptoms by 22%. These effects are attributed to PS’s ability to inhibit HPA axis overactivity and enhance gamma-aminobutyric acid (GABA) signaling, the brain’s primary inhibitory neurotransmitter.
Supports Neuroprotection in Neurodegenerative DiseasesEmerging research highlights PS’s potential in slowing the progression of neurodegenerative conditions like Alzheimer’s disease (AD) and Parkinson’s disease (PD). In AD, PS reduces the aggregation of beta-amyloid plaques (a hallmark of the disease) by stabilizing neuronal membranes and enhancing clearance of toxic proteins. A 2021 trial in Journal of Alzheimer’s Disease found that AD patients taking 300mg of PS daily for 12 months had a 28% slower decline in cognitive function than those on placebo. For PD, PS improves motor symptoms (e.g., tremors, rigidity) by supporting dopamine signaling and reducing oxidative stress in the substantia nigra (the brain region affected by PD).
Improve Exercise Recovery & EndurancePhosphatidylserine's role in regulating cortisol extends to physical performance: it reduces exercise-induced central fatigue (mental exhaustion) and enhances endurance. A 2024 study in Sports Medicine demonstrated that athletes supplementing with 200mg of PS 1 hour before exercise experienced a 10–12% increase in time to exhaustion during high-intensity cycling. Post-exercise, PS accelerated recovery by lowering cortisol levels (which contribute to muscle breakdown) and reducing perceived muscle soreness by 17% compared to placebo. These effects make PS a popular ingredient in sports nutrition products targeting endurance athletes.
Support Coagulation & Wound HealingAs a key component of platelet membranes, PS acts as a "coagulation factor" by activating the blood clotting cascade. When platelets are activated (e.g., by tissue injury), PS is exposed on the membrane surface, initiating the formation of fibrin clots. Clinical research shows that oral PS supplementation (150mg/day) can accelerate wound healing in healthy adults by 20% by enhancing platelet aggregation and collagen synthesis. This property also makes PS a valuable additive in medical foods for post-surgical recovery.

If you are looking for phosphatidylserine, Tianjiachem, as one trustworthy supplier, will always provide you not just premium products, but also solutions to help drive your business forward in the global market. Contact us today to discuss how we can collaborate and meet your specific needs

What is Phosphatidylserine?

Phosphatidylserine Benefits

Superior Bioavailability & Cellular Uptake Enhance Cognitive Function & Memory

Regulate Mood & Reduce Stress

Supports Neuroprotection in Neurodegenerative Diseases

Improve Exercise Recovery & Endurance

Support Coagulation & Wound Healing

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