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Liposomal Glutathione

CAS No.:70-18-8

Content:500g/Bag

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Product Detail

What is Liposomal Glutathione?

Liposomal glutathione (L-GSH) represents a breakthrough in nutrient delivery, addressing one of the biggest limitations of traditional glutathione (GSH): poor bioavailability. Glutathione, often called the "master antioxidant", is a tripeptide (glutamic acid, cysteine, glycine) critical for cellular redox balance, liver detoxification, and immune function. However, conventional GSH is easily degraded by stomach acid and digestive enzymes, with only 10–15% of the active compound reaching the bloodstream.

Liposomal glutathione solves this challenge by encapsulating GSH in liposomes—spherical vesicles made of phospholipid bilayers (similar to cell membranes). These liposomes act as "protective carriers": they shield GSH from gastric breakdown, enhance absorption across the intestinal barrier, and facilitate targeted delivery to cells and tissues. Moreover, unlike traditional GSH, liposomal formulations are not limited to oral use; they also excel in topical and injectable applications, expanding their utility across cosmetics, pharmaceuticals, and functional foods. Their unique structure—mimicking natural cell membranes—also reduces systemic side effects, making them a preferred choice for sensitive populations.

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Lipsomal Glutathione Benefits

Superior Bioavailability & Cellular Uptake

The lipid bilayer of liposomes protects GSH from stomach acid and pancreatic enzymes, ensuring up to 40–60% of the active ingredient reaches the bloodstream—3–5x higher than unformulated oral GSH.  Additionally, liposomes fuse directly with cell membranes, delivering GSH into the cytoplasm and mitochondria (the cell’s "powerhouses")—a critical advantage for supporting energy metabolism and reducing oxidative stress at the cellular level. 
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Enhanced Antioxidant Function & Detoxification Efficacy

By reaching higher concentrations in the liver (the body’s primary detox organ), liposomal GSH amplifies Phase II detoxification—where GSH conjugates toxins (e.g., heavy metals, environmental pollutants, pharmaceutical byproducts) for excretion. Clinical trials in adults with non-alcoholic fatty liver disease (NAFLD) showed that daily liposomal GSH supplementation (500mg) reduced liver fat content by 32% and improved liver function markers (ALT, AST) by 25% over 12 weeks—double the efficacy of traditional GSH. It also regenerates other antioxidants (vitamin C, vitamin E) more efficiently, creating a "synergistic defense network" against free radicals.

Targeted Skin Health & Anti-aging

For topical applications, liposomal GSH penetrates the skin’s stratum corneum (outer layer) 3x deeper than conventional GSH serums, delivering antioxidants directly to the dermis. This targeted delivery inhibits tyrosinase (the enzyme that produces melanin) more effectively, reducing hyperpigmentation by 22% and improving skin elasticity by 18% over 8 weeks . Oral liposomal GSH also supports skin health from within, as higher plasma GSH levels reduce collagen breakdown and protect against UV-induced oxidative damage.

Immune Support & Mitochondrial Health

Immune cells (e.g., lymphocytes, macrophages) depend on GSH to maintain viability and activity. Liposomal GSH’s enhanced cellular uptake increases GSH concentrations in immune cells by 50%, boosting lymphocyte proliferation and cytokine production (signaling molecules that coordinate immune responses). In athletes, daily liposomal GSH (600mg) reduced exercise-induced oxidative stress by 40% and improved mitochondrial function—leading to 15% better endurance compared to placebo. For elderly adults, it also mitigates age-related immune decline, reducing the risk of respiratory infections by 28%.

Reduced Gastrointestinal Irritation

Traditional oral GSH often causes nausea or abdominal cramping at high doses, as free cysteine (a breakdown product) irritates the intestinal lining. Liposomes encapsulate GSH, preventing premature breakdown and reducing direct contact with gut tissue. A 2024 consumer trial found that 92% of participants reported no gastrointestinal discomfort with liposomal GSH (1000mg/day), compared to 68% with conventional GSH.

Lipsomal Glutathione Applications

Lipsomal glutathione has versatility across oral, topical, and injectable formats—makes it a key ingredient in industries. In sports nutrition, lipsomal GSH is added to post-workout shakes to reduce muscle oxidative stress and speed recovery. It is often paired with branched-chain amino acids (BCAAs) and electrolytes for comprehensive support. In functional food and beverage, adding lipsomal GSH in "Detox" juices, collagen waters, and energy drinks together with ginger and tumeric can support liver health. Also, lipsomal GSH can be blend into dairy products and plant-based food and beverage to support gut health. As for cosmetics and cosmeceuticals, lipsomal GSH is incorporated into sunscreens to neutralize UV-induced free radicals, preventing post-sun aging (e.g., fine lines, dark spots). Its liposomal delivery ensures it remains active even after prolonged sun exposure.

If you are looking for lipsomal glutathione, Tianjiachem, as one trustworthy supplier, will always provide you not just premium products, but also solutions to help drive your business forward in the global market. Contact us today to discuss how we can collaborate and meet your specific needs




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